Week 47, 2025 · Nov 17 – Nov 23

Top 40

View all ›

Structural bio & protein design

DFT reference data refines torsion parameters and hybrid ML/MM simulation setup

Transcriptomics

Computational methods sharpen spatial positioning and clone tracing in imaging assays

Tools & infrastructure

Automated curation and standardization of small-molecule data for predictive modeling

Proteomics

Computational protein localization and secretory pathway inference from proteomic data

Structural bio & protein design

AI structure models extended to protein conformational dynamics and ensemble sampling

6 Simulation-based inference tackles intractable likelihoods in epidemic and phylodynamic…ML / AI methods

7 Sequence patterning governs peptide condensation and membrane translocationStructural bio & protein design

8 Biologically informed tokenization and patching reshape DNA language model inputsML / AI methods

9 Repeats and chromatin context shape genome architecture and regulatory variationEpigenomics

10 Inferring kinetics and time labels from nascent, untimed, and mistimed transcriptomic dataSystems biology

11 Protein language models encode nativeness, taxonomy, and memorization beyond trainingML / AI methods

12 Simulation and screening method choices are being framed as reportable design decisionsStructural bio & protein design

13 Benchmarks expose setting-dependent limits of learned protein-ligand binding and dockingTools & infrastructure

14 Learned and sparse models infer nonlinear fitness landscapes and population dynamicsGenomics

15 Deep learning decodes EEG markers of consciousness, language coherence and predictionML / AI methods

16 Pretrained genomic language models are repurposed for expression and variant predictionML / AI methods

17 Assumption-light variant and repeat inference from long and short sequencing readsGenomics

18 Browser and agent-driven tools standardize EV, transcriptomic and omics plotting workflowsTools & infrastructure

19 Protonation and ion handling shape membrane transport and penetration in MD simulationsStructural bio & protein design

20 Sequence language models probed for genome generation, ancestry, and chromatin loopsML / AI methods

Show 20 moreShow less

21 Inferring cell trajectories and tissue heterogeneity from single-cell transcriptomesSingle-cell

22 Constrained optimization for marker selection, deconvolution and cell identitySingle-cell

23 Fusing sequence, structure and graph features for multimodal interaction predictionML / AI methods

24 Deep learning links routine histology and multi-omics to cancer biomarkersML / AI methods

25 Spatial statistics and dimension reduction resolve molecular patterns in omics dataProteomics

26 Context-conditioned generators design molecules, peptides, and cell morphology profilesStructural bio & protein design

27 ML and simulations reveal GPCR activation pathways and lipid allosteric bindingStructural bio & protein design

28 Whole-brain and neural mass models tested against brain criticality and oscillationsSystems biology

29 Explicit mechanistic models of promoter, stress-response and allosteric dynamicsSystems biology

30 Assay-aware preprocessing and annotation tools for long-read and genomic interval dataTools & infrastructure

31 Software tools for batch correction, cfDNA fragment analysis and proteomics QCTools & infrastructure

32 Spectral libraries and origin-aware annotation advance LC-MS metabolomicsMetabolomics

33 Genome-scale constraint maps proto-gene precursors and duplicate-gene divergenceGenomics

34 Atlases and tools link GWAS loci and QTLs to cell types, pathways, and mechanismsGenomics

35 Stochastic models link reproductive timing, replication asymmetry, and repeat evolutionSystems biology

36 Systematic evaluation of analytical choices in single-cell RNA-seq analysisSingle-cell

37 Modelling selection on weakly deleterious mutations across genomes and virusesGenomics

38 Modeling choices alter conclusions drawn from gene regulatory network analysesSystems biology

39 Quantifying topology, calibration, and model uncertainty in phylogenetic inferenceSystems biology

40 Explicit objectives now guide single-cell lineage inference and clustering resolutionSingle-cell

Week 47, 2025 · Nov 17 – Nov 23

Top 40

DFT reference data refines torsion parameters and hybrid ML/MM simulation setup

Computational methods sharpen spatial positioning and clone tracing in imaging assays

Automated curation and standardization of small-molecule data for predictive modeling

Computational protein localization and secretory pathway inference from proteomic data

AI structure models extended to protein conformational dynamics and ensemble sampling

Sponsors