Week 46, 2025 · Nov 10 – Nov 16

Top 40

View all ›

Structural bio & protein design

AI structure models extended to protein conformational dynamics and ensemble sampling

ML / AI methods

Input selection and fusion strategies govern biomedical ML prognostic performance

Structural bio & protein design

Context-conditioned generators design molecules, peptides, and cell morphology profiles

Genomics

Genome-scale constraint maps proto-gene precursors and duplicate-gene divergence

Structural bio & protein design

Protonation and ion handling shape membrane transport and penetration in MD simulations

6 In silico mechanistic models optimize chemotherapy, ESA and cancer vaccine regimensSystems biology

7 Agents chain target discovery, pocket design, and PK simulation for therapeutic designML / AI methods

8 Inferring cell trajectories and tissue heterogeneity from single-cell transcriptomesSingle-cell

9 New callers resolve CNVs, structural variants, uniparental disomy and aneuploidy from NGSGenomics

10 Systematic evaluation of analytical choices in single-cell RNA-seq analysisSingle-cell

11 Scalable algorithms for viral discovery, read alignment, and amplicon and genome analysisGenomics

12 Spatial statistics and dimension reduction resolve molecular patterns in omics dataProteomics

13 Network and generative models of AML treatment response and drug designSystems biology

14 Quantifying topology, calibration, and model uncertainty in phylogenetic inferenceSystems biology

15 ML and simulations reveal GPCR activation pathways and lipid allosteric bindingStructural bio & protein design

16 Browser and agent-driven tools standardize EV, transcriptomic and omics plotting workflowsTools & infrastructure

17 Computational methods sharpen spatial positioning and clone tracing in imaging assaysTranscriptomics

18 Software tools for batch correction, cfDNA fragment analysis and proteomics QCTools & infrastructure

19 Protein language models encode nativeness, taxonomy, and memorization beyond trainingML / AI methods

20 Computational checks expose DNA off-targeting artifacts and novel intronic polyadenylationEpigenomics

Show 20 moreShow less

21 Machine learning and inference applied directly to raw single-trace and image dataML / AI methods

22 Deep generative and contrastive models integrate heterogeneous omics and text dataML / AI methods

23 Physical polymer models connect 3D genome organization to regulatory outputEpigenomics

24 Stochastic simulation and inference of local rules driving population-level dynamicsEpigenomics

25 Causal evaluation and graph learning for gene regulatory and disease networksML / AI methods

26 Deep learning and LLMs prioritize antimicrobial peptides and extremophile bacteriocinsML / AI methods

27 Automated curation and standardization of small-molecule data for predictive modelingTools & infrastructure

28 Learned interaction and noise structure in high-dimensional omics regression and reductionML / AI methods

29 Persistent homology and Grassmann geometry recover multiscale structure in omics dataSingle-cell

30 Benchmarks expose setting-dependent limits of learned protein-ligand binding and dockingTools & infrastructure

31 Spectral libraries and origin-aware annotation advance LC-MS metabolomicsMetabolomics

32 DFT reference data refines torsion parameters and hybrid ML/MM simulation setupStructural bio & protein design

33 Assumption-sensitive calibration of epidemic and phylodynamic modelsSystems biology

34 Hi-C-based 3D models resolve ecDNA, nuclear organization and replication timingEpigenomics

35 Stochastic models link reproductive timing, replication asymmetry, and repeat evolutionSystems biology

36 Inferring kinetics and time labels from nascent, untimed, and mistimed transcriptomic dataSystems biology

37 Explicit mechanistic models of promoter, stress-response and allosteric dynamicsSystems biology

38 MD simulations resolve dynamic conformational routes in ezrin, CENP-A, SERINC3 and ExsAStructural bio & protein design

39 Learned and sparse models infer nonlinear fitness landscapes and population dynamicsGenomics

40 Modelling selection on weakly deleterious mutations across genomes and virusesGenomics

Week 46, 2025 · Nov 10 – Nov 16

Top 40

AI structure models extended to protein conformational dynamics and ensemble sampling

Input selection and fusion strategies govern biomedical ML prognostic performance

Context-conditioned generators design molecules, peptides, and cell morphology profiles

Genome-scale constraint maps proto-gene precursors and duplicate-gene divergence

Protonation and ion handling shape membrane transport and penetration in MD simulations

Sponsors