Top 40
View all ›BACKFILLED Code and industry signals are partial for backfilled days.
Rank 1
Tools & infrastructure
Modular, reproducible software pipelines unify multi-omics and spatial data analysis
Transparent, workflow-based tools now pair GxP-ready pipelines with LLM-assisted and interactive interfaces for omics analysis.
7 preprints · 6 published · ↑ 2.8× vs 4-wk avg
Rank 2 Genomics
Reference standards and filtering set the reliability of variant calls and annotations
Recent preprints and a published study test how sequencing benchmarks, filtering rules, and uncertainty modeling shape variant-level conclusions.
5 preprints · 1 published · ↑ 2.4× vs 4-wk avg
Rank 3 Genomics
Modular tools for repeat annotation, contamination detection and genome simulation
Recent papers benchmark annotation tools and apply alignment-free and language-model approaches to repeats and replication origins in genomes.
3 preprints · 5 published · ↑ 2.1× vs 4-wk avg
Rank 4 ML / AI methods
Learned graph and edit-path representations of molecules for property prediction
January 2026 preprints and papers extend molecular representation learning to virtual edit paths, pretrained chemical language models, and knowledge graphs.
8 preprints · 3 published · ↑ 2.0× vs 4-wk avg
Rank 5 ML / AI methods
Deep learning predicts prognosis and cell states from omics and histology
Recent preprints and papers apply deep models to transcriptomic, histologic and cfDNA data for prognosis, cell typing and protein prediction.
5 preprints · 4 published · ↑ 1.7× vs 4-wk avg
Rank 6 Sequence-based tools classify SARS-CoV-2 variants and predict influenza antigenicity↑ 1.9×ML / AI methodsRank 7 Deep learning links tissue and cell morphology to gene expression and spatial domains↑ 1.8×ML / AI methodsRank 8 Learned models reconcile bulk, single-cell and multi-omic measurement layers↑ 1.7×ML / AI methodsRank 9 Protein language model embeddings extend sequence-based prediction across protein tasks↑ 1.6×ML / AI methodsRank 10 Graph and point-cloud networks model protein structure, interactions, and binding sitesStructural bio & protein designRank 11 Biophysical and plasticity constraints equipping neural network models for learning and…↑ 1.6×ML / AI methodsRank 12 Coarse-grained models link molecular structure to emergent organization in crowded cellsStructural bio & protein designRank 13 Interaction structure and stress reshape dynamical regimes of competing speciesSystems biologyRank 14 Modeling genotype-to-phenotype mapping in viral and protein evolution under selectionStructural bio & protein designRank 15 Convex polytopes and tile-based indices place tumor and omic states in bounded domainsSystems biologyRank 16 Pretrained genomic models now predict regulatory variant effects and expression tracksML / AI methodsRank 17 Reprocessing existing sequencing data to test transcript isoform and coding annotationsGenomicsRank 18 Learned predictors steer generative design toward binding and conformational objectivesStructural bio & protein designRank 19 Single-cell and regulatory profiling map disease-linked cell states across tissuesSingle-cellRank 20 Long-read and graph methods resolve repeats, haplotypes and structural variantsGenomics
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Rank 21 Host DNA reduction and integrated readouts advance microbiome sequencing analysisGenomicsRank 22 MD and enhanced sampling map unbinding and allosteric switching in drug-target complexesStructural bio & protein designRank 23 Scalable software tools for microbial genomics and metagenomics with lower memory useTools & infrastructureRank 24 Learned models convert cell imaging and tomography into quantitative phenotypic…Single-cellRank 25 Web platforms make harmonized GWAS, QTL, and cancer mutation data directly queryableTools & infrastructureRank 26 Structured-host models of pathogen spread: thresholds, coexistence and invasion wavesSystems biologyRank 27 Curated resources harmonize biomarker, drug-response, toxicity and IBD evidenceTools & infrastructureRank 28 Models for omics deconvolution, methylation imputation, and nanopore segmentationEpigenomicsRank 29 Compressed and accelerated primitives for sequencing-scale genomic analysisTools & infrastructureRank 30 Open software standardizes LC-MS/MS QC, metabolite annotation, and protease profilingTools & infrastructureRank 31 Re-sequencing and pan-genome resources link genomic variation to adaptation and breedingGenomicsRank 32 Cross-species profiling and ML models map conserved gene regulatory logicSingle-cellRank 33 Automated tools retrieve, select and manage microbial and proteomic dataTools & infrastructureRank 34 Methods link GWAS loci, gene-environment effects, and epistasis to biological mechanismGenomicsRank 35 Mechanistic tumor models test therapy and drug-tolerance dynamics in silicoSystems biologyRank 36 Learned models predict P450 metabolism sites, MS2 identifiability, and peak-node alignmentMetabolomicsRank 37 Chromosome-level assemblies relate genome structure to symbiosis and mobile elementsGenomicsRank 38 Property-guided diffusion and bridge models for RNA and peptide sequence designStructural bio & protein designRank 39 Single-cell readouts are used to reconstruct tumor clonal evolution and selectionSingle-cellRank 40 Simulations tie proton transport and hydration in complex I to disease mutationsStructural bio & protein design