Week 38, 2026 · Sep 14 – Sep 20

Top 40

ML / AI methods

Spatial models couple influenza dispersal, defective particles and interferon signalling

ML / AI methods

Interpretability Tools Recover Known Visual Selectivity in Neural Models

ML / AI methods

Protein language model embeddings enable sequence-based prediction of protein traits

Genomics

Models infer microbial and viral traits from large genomic and metagenomic datasets

Tools & infrastructure

Reproducible tools for assessing and streamlining omics data analysis workflows

6 Encoding spatial and relational structure in high-dimensional omics analysisSingle-cell

7 Adhesion, noise, and discretization shape collective and single-cell migration modelsSystems biology

8 Learned multimodal and graph representations for protein and RNA predictionML / AI methods

9 Computational models link genetic variants to RNA binding and cell-type expressionTools & infrastructure

10 Benchmark baselines and transfer conditions reshape reported gains in biological MLML / AI methods

11 Spatial and single-cell models infer multicellular motifs, regulators and disease linksSingle-cell

12 Cross-cohort tests expose limits of EEG, vocal, and transcriptomic biomarkersML / AI methods

13 Comparative genomics partitions duplication, transfer and synteny across lineagesGenomics

14 Learned models link histology and spatial transcriptomics to predict expression and nichesTools & infrastructure

15 Ensemble and free-energy methods now resolve RNA, protein and ligand binding physicsStructural bio & protein design

16 Graph storage and streaming parsers reshape population-scale variant computationTools & infrastructure

17 Fitted mechanistic models link single-cell and patient omics to regulatory dynamicsML / AI methods

18 MD ensembles and replica-exchange sampling map folding and binding pathwaysStructural bio & protein design

19 Regional brain organization metrics test normative models, criticality, and morphometrySystems biology

20 Shared embeddings fuse tissue images, spatial transcriptomes and molecular profilesML / AI methods

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21 Benchmarks and packaged pipelines standardize omics analysis toolsTools & infrastructure

22 Computational models link germinal center B cell states to antibody affinity maturationGenomics

23 Integrating diverse variant and annotation data to improve genetic risk predictionGenomics

24 LLM agents and multimodal models convert literature and spectra into molecular knowledgeTools & infrastructure

25 Pretrained generative models extend to fMRI forecasting, diagnosis, and imagerySystems biology

26 Biophysical models link ion channel, noise and modulation to network firing dynamicsSystems biology

27 Updated tools for microbial pangenomics, plasmid recovery and phylogenetic inferenceSystems biology

28 Isoform-resolved single-cell and single-molecule methods quantify transcript variantsEpigenomics

29 MD and cofolding models probe conformational states in kinases, Aβ, and HIV-1 EnvStructural bio & protein design

30 Context-aware models refine variant calling, eQTL mapping and polygenic predictionGenomics

31 MD simulations link conformational states to membrane binding and organizationStructural bio & protein design

32 Bifurcation structure and heterogeneity determine persistence beyond threshold indicesSystems biology

33 Simulations Link RNA Modifications to Conformation and Electronic StructureStructural bio & protein design

34 Simulation methods extend to cyclic peptides, non-canonical residues and polypeptoidsStructural bio & protein design

35 Sequencing and inference methods resolve nucleic acid sequence, structure, and usageGenomics

36 Reproducible environments, DNA library design and standard formats for biology toolsStructural bio & protein design

37 Benchmarks and tools expose technical biases in sequencing-based genomic assaysEpigenomics

38 Generative models steered by RL, fragments, and SMARTS for molecule and linker designStructural bio & protein design

39 Noise-driven dynamics shape neuronal firing, calcium states, and gait fluctuationsSystems biology

40 Network models nominate interventions from omics and screening dataSystems biology