Week 36, 2026 · Aug 31 – Sep 6

Top 40

Structural bio & protein design

Simulations Link RNA Modifications to Conformation and Electronic Structure

Epigenomics

Isoform-resolved single-cell and single-molecule methods quantify transcript variants

ML / AI methods

Deep learning automates microscopy and histology image analysis with less labelled data

Systems biology

Biophysical models link ion channel, noise and modulation to network firing dynamics

ML / AI methods

Interpretability Tools Recover Known Visual Selectivity in Neural Models

6 Physical and quantum-derived references inform learned models of molecular propertiesML / AI methods

7 Graph and language-model encoders advance drug-target and synergy predictionStructural bio & protein design

8 Biological priors make multi-omics deep learning interpretableML / AI methods

9 Pretrained generative models extend to fMRI forecasting, diagnosis, and imagerySystems biology

10 Graph and transformer models infer regulatory networks and disease-linked RNAsML / AI methods

11 Protein language model embeddings enable sequence-based prediction of protein traitsML / AI methods

12 Biological foundation models face scrutiny over pretraining, benchmarks, and baselinesML / AI methods

13 Simulation methods extend to cyclic peptides, non-canonical residues and polypeptoidsStructural bio & protein design

14 MD simulations link conformational states to membrane binding and organizationStructural bio & protein design

15 MD ensembles and replica-exchange sampling map folding and binding pathwaysStructural bio & protein design

16 Learned multimodal and graph representations for protein and RNA predictionML / AI methods

17 Regional brain organization metrics test normative models, criticality, and morphometrySystems biology

18 Ensemble and free-energy methods now resolve RNA, protein and ligand binding physicsStructural bio & protein design

19 Generative models steered by RL, fragments, and SMARTS for molecule and linker designStructural bio & protein design

20 Computational models link genetic variants to RNA binding and cell-type expressionTools & infrastructure

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21 Reproducible tools for assessing and streamlining omics data analysis workflowsTools & infrastructure

22 Benchmarks and tools expose technical biases in sequencing-based genomic assaysEpigenomics

23 Learned models link histology and spatial transcriptomics to predict expression and nichesTools & infrastructure

24 Correcting RNA degradation and hashtag demultiplexing in single-cell transcriptomicsSystems biology

25 Benchmarks and packaged pipelines standardize omics analysis toolsTools & infrastructure

26 Sequencing and inference methods resolve nucleic acid sequence, structure, and usageGenomics

27 Context-aware models refine variant calling, eQTL mapping and polygenic predictionGenomics

28 Multi-omic and structural data are converted into drug and target prioritization outputsGenomics

29 Computational models link germinal center B cell states to antibody affinity maturationGenomics

30 Spatial and single-cell models infer multicellular motifs, regulators and disease linksSingle-cell

31 Integrating diverse variant and annotation data to improve genetic risk predictionGenomics

32 Benchmarks probe AlphaFold model accuracy across peptides, RNA, and antibody complexesStructural bio & protein design

33 Design-aware statistical models for differential analysis of omics and imaging dataSystems biology

34 Chromosome-level assemblies link genome gigantism and gene loss to lineage evolutionGenomics

35 Bifurcation structure and heterogeneity determine persistence beyond threshold indicesSystems biology

36 Comparative genomics partitions duplication, transfer and synteny across lineagesGenomics

37 Models infer microbial and viral traits from large genomic and metagenomic datasetsGenomics

38 Updated tools for microbial pangenomics, plasmid recovery and phylogenetic inferenceSystems biology

39 Noise-driven dynamics shape neuronal firing, calcium states, and gait fluctuationsSystems biology

40 Graph storage and streaming parsers reshape population-scale variant computationTools & infrastructure