Week 27, 2026 · Jun 29 – Jul 5

Top 40

ML / AI methods

Interpretability Tools Recover Known Visual Selectivity in Neural Models

ML / AI methods

Spatial models couple influenza dispersal, defective particles and interferon signalling

Genomics

Computational models link germinal center B cell states to antibody affinity maturation

ML / AI methods

Learned latents steer protein conformations and encode evolutionary structure

Genomics

Comparative genomics partitions duplication, transfer and synteny across lineages

6 Biological priors make multi-omics deep learning interpretableML / AI methods

7 Benchmarks for AI virtual cell models are being tested for scientific validityML / AI methods

8 Internal ground truths benchmark RNA-seq transcript and expression inference toolsGenomics

9 LLM agents and multimodal models convert literature and spectra into molecular knowledgeTools & infrastructure

10 Protein language model embeddings enable sequence-based prediction of protein traitsML / AI methods

11 Fitted mechanistic models link single-cell and patient omics to regulatory dynamicsML / AI methods

12 New tools speed variant annotation, GWAS, and epigenomic and cytometry analysisTools & infrastructure

13 Graph and attention models fuse spatial and single-cell multi-omics dataML / AI methods

14 Correcting RNA degradation and hashtag demultiplexing in single-cell transcriptomicsSystems biology

15 Chromosome-level assemblies link genome gigantism and gene loss to lineage evolutionGenomics

16 MD and cofolding models probe conformational states in kinases, Aβ, and HIV-1 EnvStructural bio & protein design

17 Reduced recurrent models reproduce complex dynamics across neural and molecular systemsSystems biology

18 Simulation methods extend to cyclic peptides, non-canonical residues and polypeptoidsStructural bio & protein design

19 Reproducible environments, DNA library design and standard formats for biology toolsStructural bio & protein design

20 Graph and language-model encoders advance drug-target and synergy predictionStructural bio & protein design

Show 20 more

21 MD simulations link conformational states to membrane binding and organizationStructural bio & protein design

22 Learned models link histology and spatial transcriptomics to predict expression and nichesTools & infrastructure

23 Benchmarks and tools expose technical biases in sequencing-based genomic assaysEpigenomics

24 Generative models steered by RL, fragments, and SMARTS for molecule and linker designStructural bio & protein design

25 Reproducible tools for assessing and streamlining omics data analysis workflowsTools & infrastructure

26 Graph neural networks model molecular interactions, drug synergy and disease driversSystems biology

27 Models link non-genetic B cell state dynamics to antibody affinity maturationSystems biology

28 Models infer microbial and viral traits from large genomic and metagenomic datasetsGenomics

29 Spatial and single-cell models infer multicellular motifs, regulators and disease linksSingle-cell

30 Network models nominate interventions from omics and screening dataSystems biology

31 Noise-driven dynamics shape neuronal firing, calcium states, and gait fluctuationsSystems biology

32 Encoding spatial and relational structure in high-dimensional omics analysisSingle-cell

33 MD ensembles and replica-exchange sampling map folding and binding pathwaysStructural bio & protein design

34 Updated tools for microbial pangenomics, plasmid recovery and phylogenetic inferenceSystems biology

35 Biophysical models link ion channel, noise and modulation to network firing dynamicsSystems biology

36 Integrating diverse variant and annotation data to improve genetic risk predictionGenomics

37 Sequencing and inference methods resolve nucleic acid sequence, structure, and usageGenomics

38 Isoform-resolved single-cell and single-molecule methods quantify transcript variantsEpigenomics

39 Multi-omic and structural data are converted into drug and target prioritization outputsGenomics

40 Ensemble and free-energy methods now resolve RNA, protein and ligand binding physicsStructural bio & protein design