Week 24, 2026 · Jun 8 – Jun 14

Top 40

Systems biology

Regional brain organization metrics test normative models, criticality, and morphometry

ML / AI methods

Learned predictors score protein interactions, variant effects, and peptide activity

Tools & infrastructure

Reproducible tools for assessing and streamlining omics data analysis workflows

Genomics

Chromosome-level assemblies link genome gigantism and gene loss to lineage evolution

Tools & infrastructure

Computational models link genetic variants to RNA binding and cell-type expression

6 Benchmarking segmentation and synthetic ground truth for 3D tissue and organoid imagingML / AI methods

7 New tools speed variant annotation, GWAS, and epigenomic and cytometry analysisTools & infrastructure

8 Recovering single-cell kinetics and trajectories from static and noisy measurementsML / AI methods

9 Physical and quantum-derived references inform learned models of molecular propertiesML / AI methods

10 Ancient and phased human genomes test selection and imputation inference methodsGenomics

11 Comparative genomics partitions duplication, transfer and synteny across lineagesGenomics

12 Spatial and single-cell models infer multicellular motifs, regulators and disease linksSingle-cell

13 Network models nominate interventions from omics and screening dataSystems biology

14 Graph and language-model encoders advance drug-target and synergy predictionStructural bio & protein design

15 Biological foundation models face scrutiny over pretraining, benchmarks, and baselinesML / AI methods

16 Learned multimodal and graph representations for protein and RNA predictionML / AI methods

17 Multi-omic and structural data are converted into drug and target prioritization outputsGenomics

18 Learned models link histology and spatial transcriptomics to predict expression and nichesTools & infrastructure

19 Correcting RNA degradation and hashtag demultiplexing in single-cell transcriptomicsSystems biology

20 Bifurcation structure and heterogeneity determine persistence beyond threshold indicesSystems biology

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21 Reduced recurrent models reproduce complex dynamics across neural and molecular systemsSystems biology

22 Graph storage and streaming parsers reshape population-scale variant computationTools & infrastructure

23 Simulations Link RNA Modifications to Conformation and Electronic StructureStructural bio & protein design

24 LLM agents automate bioinformatics workflows with verifiable, grounded outputsML / AI methods

25 MD ensembles and replica-exchange sampling map folding and binding pathwaysStructural bio & protein design

26 Generative models steered by RL, fragments, and SMARTS for molecule and linker designStructural bio & protein design

27 Design-aware statistical models for differential analysis of omics and imaging dataSystems biology

28 Deep learning automates microscopy and histology image analysis with less labelled dataML / AI methods

29 Graph neural networks model molecular interactions, drug synergy and disease driversSystems biology

30 Noise-driven dynamics shape neuronal firing, calcium states, and gait fluctuationsSystems biology

31 MD simulations link conformational states to membrane binding and organizationStructural bio & protein design

32 Encoding spatial and relational structure in high-dimensional omics analysisSingle-cell

33 Reproducible environments, DNA library design and standard formats for biology toolsStructural bio & protein design

34 Context-aware models refine variant calling, eQTL mapping and polygenic predictionGenomics

35 Computational models link germinal center B cell states to antibody affinity maturationGenomics

36 Simulation methods extend to cyclic peptides, non-canonical residues and polypeptoidsStructural bio & protein design

37 Models infer microbial and viral traits from large genomic and metagenomic datasetsGenomics

38 Benchmarks and tools expose technical biases in sequencing-based genomic assaysEpigenomics

39 Isoform-resolved single-cell and single-molecule methods quantify transcript variantsEpigenomics

40 Internal ground truths benchmark RNA-seq transcript and expression inference toolsGenomics