#27 · Systems biology

Models link quorum-sensing evolution and cell morphology to bacterial community dynamics

The dominant thread is mathematical and agent-based modeling of bacterial populations, where trait evolution and community stability are analyzed as outcomes of population structure and environment. One preprint shows that quorum-sensing permeability evolves collectively, with environmental switching frequency setting the trait split and coexistence arising at symmetry. A published study combines agent-based simulations with a drift-diffusion model to show that cell morphology shapes boundary dynamics, fixation, and coexistence in model bacterial communities. A separate preprint partitions viral fitness into replicative, infective, and dispersal components to explain HCV persistence regimes, a related fitness-decomposition framing applied to a viral system. Taken together, the new contribution is the explicit treatment of environmental stochasticity and morphological geometry as determinants of evolutionary and ecological outcomes in bacterial populations.