Top 40
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Single-cell
Spatial and single-cell omics methods separate modeling choices from inferred structure
Recent spatial and single-cell omics work frames each method around what it separates, from isoform usage versus abundance to target leakage in benchmarks.
ML / AI methods
Joint generative models co-design RNA, protein and DNA sequences with structure
Preprints pair unified enzymatic reaction benchmarks with joint sequence-structure generation, while a published model advances enzyme function prediction.
Structural bio & protein design
Benchmarks and tools probe biomolecular structure prediction beyond single static models
Recent preprints and publications benchmark co-folding predictors and release restraint, decoy, and pocket-detection tools for biomolecular ensembles.
Single-cell
Spatial omics tools add velocity, circular statistics and per-spot instability scoring
Recent items extend spatial and single-cell analysis to spatial RNA velocity, instability scoring, and standardized cell ontologies.
Systems biology
Mechanistic models infer gene networks and perturbation responses from omics data
New methods couple mechanistic structure with statistical inference for single-cell, microbiome, and multi-omic datasets.