Top 40
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Genomics
Copy number, indel, and mutational-process calling across tissue and cancer genomes
Benchmarks and new tools now resolve copy number, indels, haplotype-phased somatic mutations, and mutational signatures at tissue scale.
Structural bio & protein design
Field-neuron coupling and traveling waves reveal spatiotemporal propagation in cortex
Realistic connectivity and scalable field-coupled solvers now enable mechanistic modeling of propagation across neuronal and cortical scales.
Transcriptomics
Pairing isoform-resolved and spatial transcriptomics with built-in analytic diagnostics
Long-read and spatial workflows now resolve isoforms and tissue architecture at single-cell scale, and benchmarks are testing their reliability.
Systems biology
Membrane and condensate interfaces govern nanoscale transport in simulation studies
Coarse-grained and all-atom simulations now resolve how membranes, condensates, and PEGylated nanoparticles set transport and partitioning at interfaces.
Structural bio & protein design
Learned models infer directional protein flexibility and conformational motion
Recent preprints extend learned representations from static structures to directional motion, cryo-EM state transitions and co-folding mechanisms.