Top 40
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Transcriptomics
Frameworks integrate spatial, histology, and single-cell transcriptomic data
Spatial and single-cell transcriptomics are now integrated with histology, mechanics, and time-course data in benchmarked computational frameworks.
Structural bio & protein design
Physics-based and learned models sample disordered protein and nucleic acid ensembles
Recent preprints pair refined all-atom and coarse-grained force fields with flow-matching generators for disordered and nucleic acid systems.
ML / AI methods
Geometry-aware models extend binding and activity prediction across molecule classes
Recent work tests structure-derived and sequence-only models under cold-start, leave-target-out, and cross-species evaluation splits.
Epigenomics
Normalization and differential testing tools for chromatin and regulatory genomics data
Recent methods target technical bias, multiple testing, and interpretability in ATAC-seq, Hi-C, methylation, and regulatory network analyses.
Tools & infrastructure
Software tools for reproducible analysis of genomic, epigenomic, and imaging data
Recent publications release tools for cross-species atlas comparison, RNA modification mining, HiChIP processing, and bioimage analysis.