Top 40
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Genomics
Pangenome graphs and variant-effect models sharpen variant interpretation across genomes
Pangenome catalogs, multiomic atlases, and AlphaGenome-based tools now offer tissue- and haplotype-resolved routes from variant to function.
Systems biology
Synaptic delays, phase-targeted pulses and disease models shape neural oscillations
Spiking and neural mass models now link synaptic delays, phase-dependent pulsing, and beta bursts to oscillatory control in disease.
Structural bio & protein design
ML maps binder and antibody sequences to binding, developability, and design outcomes
Blinded benchmarks and experimentally anchored datasets now test whether sequence-based models generalize beyond their training distributions.
ML / AI methods
Pretrained sequence model embeddings drive residue- and protein-level predictions
Recent preprints apply ESM-2, ESM3, and InterPLM features to enzyme, protein, and neuropeptide classification, extending representation-based prediction.
ML / AI methods
Pretrained and Bayesian models for molecular, protein, and genomic prediction tasks
Recent preprints benchmark foundation, Bayesian, and LLM models against classical ML for protein, molecular, and genomic tasks under rigorous evaluation.