Top 40
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Transcriptomics
Inferring time-resolved regulatory dynamics from single-cell and spatial transcriptomics
Recent frameworks jointly model time, lineage and space to infer regulatory dynamics from single-cell and spatial transcriptomic data.
ML / AI methods
Encoding Biological Priors as Structural Constraints in Predictive Models
Recent papers embed curated gene ontologies, biomarker priors, and molecular structure into learning models to constrain and interpret predictions.
ML / AI methods
Bayesian and probabilistic models for interpreting high-dimensional omics and microbiome…
Recent bioinformatics and preprint work applies Bayesian shrinkage, uncertainty quantification and interpretable learning to multi-omics and microbiome…
Structural bio & protein design
Deep learning models are being repurposed for stability, fitness and binding predictions
Recent preprints and journal papers apply protein language, inverse-folding and co-folding models to variant effect and interaction prediction.
Tools & infrastructure
Established genomics algorithms wrapped in interactive, portable, and automated tools
Pangenome graphs and large alignment files call for interactive viewers, compressed formats, and automated workflows usable beyond specialists.