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BACKFILLED Code and industry signals are partial for backfilled days.

Rank 1

ML / AI methods

Structural priors fused with multimodal inputs predict clinical and regulatory outcomes

Recent preprints and publications pair multi-omics, sequence, and graph structure with specific predictive endpoints, from drug response to CAR T outcomes.

4 preprints · 4 published · ↑ 2.3× vs 4-wk avg
Rank 2

Systems biology

Inferring gene regulatory networks from expression, epigenomic and perturbation data

Enhancer-gene encyclopedias and cross-method benchmarks now test how far inferred regulatory networks can be trusted.

7 preprints · 2 published · ↑ 2.3× vs 4-wk avg
Rank 3

Genomics

Large genome panels resolve lineage history, regulatory networks, and evolutionary rates

Large genome panels and alignment, network, and mediation methods now enable cross-species inference of origin, selection, regulation, and evolutionary tempo.

2 preprints · 3 published · ↑ 2.1× vs 4-wk avg
Rank 4

Genomics

Simulation and sequencing methods probe alternative nucleic acid conformations

Recent preprints and papers pair molecular dynamics, nanopore sequencing and machine learning to resolve non-B DNA and RNA structure.

3 preprints · 2 published · ↑ 2.0× vs 4-wk avg
Rank 5

Tools & infrastructure

Sequencing tools infer molecular features from reads, validated against benchmarks

Recent preprints and papers present Docker-deployable, VCF-based and GUI pipelines for single-cell, somatic and targeted tumor RNA-seq analysis.

3 preprints · 4 published · ↑ 1.8× vs 4-wk avg