Top 40
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Single-cell
Single-cell tools resolve transcript and regulatory architecture across tissues
Recent preprints and papers add spatial CRISPR, niche-level communication analysis and multimodal tissue integration to single-cell profiling.
Single-cell
New methods for single-cell perturbation, chromatin and multi-omic regulatory analysis
Perturb-seq power design, causal mediation analysis, and multimodal chemical screens now resolve regulatory mechanisms at single-cell resolution.
Structural bio & protein design
Deep learning methods expand RNA and protein sequence and structure design
Recent preprints report generative and geometric deep learning methods for RNA, protein, and nucleic acid design and docking.
Tools & infrastructure
New algorithms advance viral alignment, RNA structure, protein comparison, and k-mer sets
Four May 2026 preprints present alignment and comparison methods for viral genomes, RNA structures, protein structures, and k-mer spectra.
Genomics
Sequence models link viral sequence features to host origin and immune escape
Predictive sequence-level models now pair evolutionary inference with explicit host, protein, and vaccine-effectiveness readouts across viral taxa.