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Single-cell
Pipelines resolve ambient RNA, allele-specific reads and transcript-level assignment
Growing single-cell and multi-assay datasets demand explicit correction of ambient RNA, doublets and mapping ambiguity in nucleic acid readouts.
Single-cell
Geometric and spatial context coupled to single-cell dynamics and spatial inference
Recent preprints couple local geometry and spatial context to single-cell dynamics, fate, and tissue-level inference.
Tools & infrastructure
Harmonized public omics resources enable cross-layer reanalysis of disease and cell data
Heterogeneous public single-cell, long-read and variant datasets are now being packaged into searchable, reproducible resources and pipelines.
Genomics
Chromosome-scale reference genomes across pupfish, oyster, leech, wasp, and nematode…
Chromosome-scale assemblies now serve as comparative and functional reference resources for non-model animals, increasingly paired with transcript and…
Tools & infrastructure
Domain-constrained LLM agents verify tool execution across biomedical workflows
Four recent preprints report LLM agents with verifiable tool execution for traditional medicine, imaging, breeding, and CRISPR guide design.