Top 40
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Genomics
Benchmarks reveal how somatic and structural variant callers perform across platforms
Standardized truth sets and cross-platform evaluations are now defining how somatic and structural variants are benchmarked in cancer genomes.
Single-cell
Frameworks infer cell-state and spatial structure from single-cell transcriptomes
Recent preprints and publications extend single-cell and spatial inference to aging, lineage, isoform, and multi-slice atlas scales.
Tools & infrastructure
Reference-light methods advance microbial taxonomic profiling and genome-based typing
Recent preprints apply ANI, breadth statistics and learned models to microbial genomes and metagenomes at database scale.
Structural bio & protein design
Stricter benchmarks and calibrated confidence reshape structure-based pose prediction
Recent preprints pair held-out benchmarks and prospective tests with calibrated AlphaFold confidence for interface quality and pose-level prediction.
ML / AI methods
Learned and accelerated sequence methods for repeats, mobile elements and gene families
Learned sequence models and accelerated alignment are now applied directly to repeat-rich and mobile genomic elements across large datasets.