Top 40
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Transcriptomics
New frameworks resolve gene programs and clustering instability in spatial omics
Multi-slice spatial and isoform-resolved datasets now demand methods that separate biological programs from analytical instability.
ML / AI methods
Genomic language models are benchmarked across DNA classification and design tasks
Recent preprints test DNA and nucleotide language models against fixed splits, frozen-embedding baselines, and controlled held-out sets.
Systems biology
Models encode finite resource constraints in metabolism, growth and spatial organization
Predictive models now encode constraints, trade-offs and spatial heterogeneity that shape how cells partition finite resources.
Single-cell
Identifiability and sample-size limits in single-cell perturbation inference
Perturbation screens and single-cell state-transition data now require explicit identifiability, cell-quota, and leakage-aware evaluation criteria.
Systems biology
Computational inference of gene regulatory networks from single-cell and omics data
Single-cell perturbation and multi-omic datasets now support network models that infer regulatory logic and sample-specific interactions.