Top 40
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Systems biology
Mechanistic and causal models for dynamic, zero-inflated, and spatial omics data
Recent methods address time-varying exposures, zero-inflated microbiome mediators, and perturbation responses in single-cell and spatial data.
Single-cell
Single-cell and omics tools adapt established methods to new data and noise regimes
Recent preprints and publications test method behavior and port established single-cell frameworks to new modalities and noise regimes.
Tools & infrastructure
Scalable sketching and standardized pipelines reshape large-scale sequence data analysis
Public sequence archives now span millions of genomes and metagenomes, demanding sketch-based search and standardized reference handling.
Structural bio & protein design
Structure-conditioned models predict antibody, pocket, and ligand interactions
Recent bioinformatics papers and preprints extend structure-aware deep learning to antibody design, binding-site detection, and molecule generation.
Structural bio & protein design
Ensemble sampling and simulation scoring improve antibody-antigen complex prediction
Complex prediction accuracy now depends on combining multi-source sampling with physics-based stability checks and learned candidate selection.