Top 40
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Structural bio & protein design
Tools for macromolecular structure preparation, comparison, search and model selection
Recent releases pair fast, memory-safe implementations with structure preparation, RNA modeling, comparison, search and complex model selection.
Genomics
k-mer and language-model methods expand genome and protein functional annotation
Recent preprints and papers extend annotation to pangenome graphs, bacterial protein clusters and proteome-wide phylogenomics without reference alignment.
Proteomics
Reference standards and proteomes map eukaryotic genome and organelle diversity
Expanding eukaryotic reference genomes and organelle proteomes now enable standardized comparisons across deep phylogenetic breadth.
Single-cell
Joint latent spaces integrate single-cell, spatial and bulk omics across modalities
Deep generative and optimal-transport models now align heterogeneous single-cell and bulk modalities, including unpaired and histology-derived data.
Systems biology
Network and regulatory atlases map disease-linked molecular architecture across scales
Higher-resolution interactome, single-cell, and 3D genome maps now link disease proteins and regulatory elements to specific cellular contexts.