Top 40
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Genomics
Truth-anchored variant calling extends to long reads, pangenomes and nonmodel genomes
Long-read and pangenome-based pipelines are being benchmarked against reference truth sets across germline, somatic and nonmodel applications.
Transcriptomics
Computational methods infer unmeasured cell composition from spatial transcriptomics
Recent work extends spatial transcriptomics inference to whole-slide reconstruction, multi-platform integration, and mechanical co-registration.
Systems biology
Omics statistics increasingly model confounders and compositionality explicitly
Recent methods address confounding, compositionality, and high-dimensional dependence with formal inference, and benchmarking now compares them across multiple…
ML / AI methods
Graph and contrastive models integrate spatial omics with histology and imaging data
Recent items pair spatial transcriptomics, proteomics, histology and neuroimaging with graph and contrastive learning for domain and cell-type inference.
Transcriptomics
Workflow choices shape isoform-resolved and single-cell transcriptome readouts
Long-read and single-cell transcriptomics now depend on modular pipelines whose annotation, normalization, and QC choices affect downstream results.