Top 40
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Systems biology
Network models of neural activity and oscillations explain disease-linked brain dynamics
Neural mass, spiking E-I, and epidemic-style brain network models now link oscillation mechanisms to Alzheimer's and Parkinson's observations.
Transcriptomics
Learned models infer spatial and live-cell transcriptomic states from indirect data
Spatial transcriptomics and live-cell imaging now pair with deep learning and geometric models to infer unmeasured molecular states.
ML / AI methods
Structure-aware deep learning models advance RNA modification and efficacy prediction
Pretrained RNA encoders and structure-aware architectures are now transferred across siRNA efficacy and m6A/m6Am site prediction.
Structural bio & protein design
Protein language models guide co-design, fitness alignment, and solubility prediction
Recent work extends protein language models from property prediction to generative co-design and conformational ensemble generation.
ML / AI methods
Deep learning maps peptide, TCR, and protein sequences to functional readouts
Recent work tests whether sequence-to-function models generalize to unseen peptides and modifications and couple prediction to experimental validation.