Top 40
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Structural bio & protein design
Web servers package structure-based methods for modeling, docking, and protein engineering
Recent web servers and a remote homology benchmark extend structure-based prediction, docking, and comparative analysis to broader user workflows.
Genomics
Pangenome graphs and genome benchmarks advance bacterial resistance and typing analysis
Recent preprints and papers apply pangenome and assembly graphs to resistance genes, typing, and taxonomy across bacterial genomes.
ML / AI methods
Sequence foundation models are tested for biosecurity, fitness, and structure tasks
Foundation models trained on sequences are now benchmarked for biosecurity screening, fitness prediction, and sequence-to-function transfer.
Genomics
Computational models score variant pathogenicity across coding and structural variation
Recent tools combine in silico predictions, protein language models, and patient or cohort-level evidence to refine variant interpretation.
ML / AI methods
Deep models integrate multimodal omics and clinical data for patient outcome prediction
Recent preprints and one published model apply attention and variational architectures to heterogeneous patient data for prediction.