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BACKFILLED Code and industry signals are partial for backfilled days.

Rank 1

Epigenomics

Sequence and network models advance prediction of TF binding and chromatin insulation

June 2026 preprints and papers apply deep learning and graphical models to regulatory prediction tasks.

5 preprints · 3 published · ↑ 3.7× vs 4-wk avg
Rank 2

Single-cell

Benchmarks expose method-dependent variability in single-cell and spatial transcriptomics

Preprints and published work now quantify analytic instability in single-cell and spatial workflows while proposing corrective and interpretive methods.

9 preprints · 5 published · ↑ 2.7× vs 4-wk avg
Rank 3

ML / AI methods

Multimodal pretrained models learn molecular, protein, and cellular representations

Recent work fuses graph, text, sequence, structure, and microscopy views with noise-aware and retrieval-based training for property and interaction prediction.

6 preprints · 3 published · ↑ 2.7× vs 4-wk avg
Rank 4

Structural bio & protein design

Learned models now predict binding, design and specificity from structure and sequence

Several new predictors for binding, design and property tasks rely on protein language model embeddings or 3D structure inputs.

5 preprints · 2 published · ↑ 2.7× vs 4-wk avg
Rank 5

Transcriptomics

Computational bridging of spatial measurements across modalities, platforms and species

Foundation-model priors and optimal transport now connect routine H&E histology to spatial transcriptomic and proteomic measurements.

4 preprints · 4 published · ↑ 2.6× vs 4-wk avg