Top 40
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ML / AI methods
Generative models span peptide, TCR, binder, antibody and PROTAC design
Recent preprints pair conditional generators across peptides, TCRs, antibodies, and PROTACs with interpretability and structured readouts.
Structural bio & protein design
Computational models predict cancer pathway, antibody kinetics and codon design outcomes
Recent preprints apply GPU simulation, metadynamics and Bayesian networks to forecast molecular and pathway behavior in silico.
Genomics
Genome-scale inference of bacterial resistance evolution and thermal adaptation
Genome-scale bacterial datasets now support genotype-phenotype and evolutionary inference beyond single-gene or single-lineage analyses.
Genomics
New computational methods map noncoding variants and interaction effects to genes
Biobank-scale datasets and GPU-accelerated algorithms now make genome-wide interaction, colocalisation, and mediation analyses computationally tractable.
Single-cell
Computational frameworks link spatial, single-cell and histology data across tissues
Spatial and single-cell resources now span histology inference, unpaired multi-omics integration, and LLM-driven long-read analysis.