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Rank 1

Systems biology

Genome-wide data curation and evolutionary inference across viral and bacterial pathogens

Newly reported tools and analyses address deduplication, artifact masking, and recombination in pathogen genome collections spanning thousands of isolates.

2 preprints · 3 published · ↑ 2.7× vs 4-wk avg
Rank 2

Genomics

Comparative genomics ties regulatory evolution to lineage-specific innovation

3 preprints · 4 published · ↑ 2.5× vs 4-wk avg
Rank 3

ML / AI methods

Structure-derived objectives guiding deep models for binder and compound prioritization

Recent preprints couple predicted protein structures with learned objectives for binder ranking, affinity prediction, and conformational benchmarking.

5 preprints · 3 published · ↑ 2.4× vs 4-wk avg
Rank 4

Genomics

Genome-scale tools refine orthology, annotation and contamination removal

Recent preprints benchmark new orthogroup, annotation, decontamination and search-space methods against established tools in June 2026.

5 preprints · 1 published · ↑ 2.4× vs 4-wk avg
Rank 5

ML / AI methods

Machine learning models span antimicrobial, toxicity, PROTAC, and siRNA design tasks

Preprints now pair graph, hypergraph, and generative models with ADMET, toxicity, and phenotypic endpoints for compound prioritisation.

7 preprints · 1 published · ↑ 2.3× vs 4-wk avg