Top 40
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Single-cell
New computational tools decode gene regulation and cell identity from single-cell omics
Recent work pairs new deep generative and network methods with benchmarking and reanalysis, testing the reliability of single-cell inference tools.
Tools & infrastructure
Software tools for variant calling, chromatin state, and splicing from sequencing data
Multiple June 2026 publications release reproducible Snakemake and Nextflow pipelines spanning variant, chromatin, and splicing analysis.
Transcriptomics
Graph and contrastive deep learning infers spatial gene expression and tissue domains
Histology and spatial transcriptomics are now paired with graph, contrastive, and attention models to predict expression and resolve tissue domains.
ML / AI methods
Graph neural networks extend structure-based prediction across drug discovery and omics
Recent preprints and publications apply graph neural networks to druggability, PROTAC degradability, methylation, and multi-omics prediction tasks.
Structural bio & protein design
Protein language models and generative models predict and design biomolecular properties
Recent preprints and papers pair pretrained protein and DNA language model features with task-specific heads, adapters, and generative models.