Top 40
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Structural bio & protein design
Benchmarks expose leakage and inconsistent evaluation in biological prediction tools
Open benchmarks of gene prediction, binding free energy, and backbone generation methods now test tools against blinded or unified evaluation frameworks.
ML / AI methods
Protein language model and structure embeddings drive diverse sequence prediction tasks
Pretrained sequence and structure embeddings are now transferred across protein, mRNA, and genomic prediction tasks.
Structural bio & protein design
MD conformational ensembles guide ligand and allosteric site selection
Recent studies pair MD-derived ensembles with binding free energy, RNA-ligand docking, and ligand shape matching benchmarks.
Single-cell
Batch correction, imputation and splicing benchmarks advance single-cell omics analysis
Preprints and papers target batch effects, missing values and transcript assembly that constrain single-cell and proteomic data interpretation.
Single-cell
Single-cell multi-omics maps age-linked T-cell and endometrial disease states
Atlas-scale single-cell and multi-omic profiling now links aging, disease severity, and senescence to cell-state-specific transcriptional programs.