TrendBio

What moved in computational biology today

bioRxiv, arXiv, PubMed, GitHub and industry. Updated .

Top 40

View all ›

BACKFILLED Code and industry signals are partial for backfilled days.

Rank 1

Tools & infrastructure

LLM agents orchestrate domain bioinformatics tools with auditable, checkable execution

Recent preprints apply LLM agents to proteomics, transcriptomics, gene-level evidence, and literature-derived databases with traceable outputs.

7 preprints · 3 published · ↑ 2.5× vs 4-wk avg
Rank 2

Tools & infrastructure

Single-cell and spatial resources integrate cell typing, CNV and methylation markers

Single-cell and spatial tools now combine transcriptomic, CNV and methylation data to resolve malignant and cell-type identity across platforms.

6 preprints · 9 published · ↑ 2.4× vs 4-wk avg
Rank 3

ML / AI methods

Benchmark baselines and transfer conditions reshape reported gains in biological ML

Recent preprints and a published model paper test whether reported gains in biological ML hold under stricter baselines and held-out contexts.

7 preprints · 1 published · ↑ 1.7× vs 4-wk avg
Rank 4

ML / AI methods

Biological priors inform models predicting expression from histology and perturbations

Foundation models and graph-based architectures now encode tissue, spatial, and perturbation context to predict transcriptomic and proteomic states.

11 preprints · 3 published · ↑ 1.6× vs 4-wk avg
Rank 5

Genomics

Single-cell QTL mapping resolves cell-type and temporal control of gene regulation

Expanded single-cell, tandem repeat, and circadian eQTL datasets now enable cell-type and time-resolved variant effect mapping at scale.

2 preprints · 7 published · ↑ 1.7× vs 4-wk avg